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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRP12
All Species:
29.39
Human Site:
S380
Identified Species:
64.67
UniProt:
Q5JTH9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JTH9
NP_001138586.1
1297
143702
S380
A
L
Y
D
Y
V
P
S
E
N
D
L
Q
P
L
Chimpanzee
Pan troglodytes
XP_001161750
1295
143474
S380
A
L
Y
D
Y
V
P
S
E
N
D
L
Q
P
L
Rhesus Macaque
Macaca mulatta
XP_001102543
1293
142811
S377
A
L
Y
D
Y
V
P
S
E
N
D
L
Q
P
L
Dog
Lupus familis
XP_850930
1324
146892
S405
A
L
Y
D
Y
I
P
S
E
N
D
L
Q
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5B0
1295
143113
S381
A
L
Y
D
Y
V
P
S
E
N
D
L
Q
P
L
Rat
Rattus norvegicus
XP_001054805
1232
136504
K380
A
A
A
T
Q
T
L
K
E
I
L
R
E
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKD5
1294
144034
S383
A
L
Y
D
Y
V
P
S
A
N
D
L
Q
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001025447
1283
142914
S377
A
L
Y
D
Y
V
P
S
E
N
D
L
Q
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYA7
1384
153539
S417
H
E
Y
R
P
D
K
S
D
I
R
Q
T
I
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_497319
1334
147629
S380
A
L
R
Q
L
G
A
S
V
T
D
V
T
V
T
Sea Urchin
Strong. purpuratus
XP_792353
1431
157647
G443
A
L
Y
D
Y
Q
P
G
E
S
D
S
Q
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
92.2
90.1
N.A.
90.7
85.4
N.A.
N.A.
71.1
N.A.
61.8
N.A.
30.2
N.A.
26.6
44.3
Protein Similarity:
100
99.6
94.5
93.9
N.A.
94.9
90.2
N.A.
N.A.
84.5
N.A.
79.7
N.A.
50.2
N.A.
45.5
64.7
P-Site Identity:
100
100
100
93.3
N.A.
100
13.3
N.A.
N.A.
93.3
N.A.
100
N.A.
13.3
N.A.
26.6
60
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
93.3
N.A.
100
N.A.
20
N.A.
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
91
10
10
0
0
0
10
0
10
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
73
0
10
0
0
10
0
82
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
73
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
19
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% K
% Leu:
0
82
0
0
10
0
10
0
0
0
10
64
0
0
64
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
73
0
0
0
0
0
0
64
0
% P
% Gln:
0
0
0
10
10
10
0
0
0
0
0
10
73
0
0
% Q
% Arg:
0
0
10
10
0
0
0
0
0
0
10
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
82
0
10
0
10
0
0
0
% S
% Thr:
0
0
0
10
0
10
0
0
0
10
0
0
19
0
10
% T
% Val:
0
0
0
0
0
55
0
0
10
0
0
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
82
0
73
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _